Drug Trials Find Xolair May Help With Milk Allergy Treatment

Clinical trials for the drug Xolair (omalizumab) found that although it did not work as expected, it did have a surprising effect that could prove useful in future immunotherapy treatments for milk allergies.

Why Did You Visit This Website?
I have a peanut and/or nut allergy
100%
A family member has a peanut and/or nut allergy
0%
I might have a peanut and/or nut allergy
0%
I am just looking for information
0%
Total votes: 3

The trials were conducted to test omalizumab's effectiveness as a way to improve oral immunotherapy effectiveness by dampening the allergic reaction to cow's milk. The desired effect, however, did not prove conclusive in the trials. Instead, researchers found that Xolair was likely reducing the effects of adverse allergic reactions to cow's milk during the study.

The surprising result opens new avenues for research and potential treatment options using Xolair.

Xolair could help reduce the "build up phase" time during OIT.

During oral immunotherapy, the first phase of treatment is to slowly build a tolerance to very small amounts of the allergen. In the case of milk allergy, this usually means small drops of milk being introduced in controlled circumstances so that adverse reactions can be quickly dealt with by medical staff.

When testing omalizumab in trials, researchers assembled 57 children with milk allergies. Half were given the drug before and during the OIT while the other half were given a placebo. During the build-up phase of the therapy, among those children given Xolair, only one had a severe reaction to milk that required epinephrine. Among the children who did not receive it, eight of them had severe reactions.

Dr. Hugh Sampson, director of the Jaffe Food Allergy Institute at New York’s Icahn School of Medicine at Mount Sinai, who lead the study, believes that this opens a new avenue for research into the drug. He acknowledges the limitations of the study and its interesting and unexpected result, but more work will be required to prove efficacy as an OIT additive.

Source: Allergic Living

Community

Latest Post by blprestangen Mon, 09/16/2019 - 1:06pm
Comments: 12
Latest Post by mom2two Mon, 09/16/2019 - 1:03pm
Comments: 18
Latest Post by Kathryn Mon, 09/16/2019 - 1:02pm
Comments: 7

More Articles

Do you think you may have a food intolerance? Many people make it to adulthood without realizing they have a food intolerance because they have...

With only a casual understanding of Oral Immunotherapy (OIT) some people assume that simply feeding children a bit of their problem food, in order...

Babies usually show the same peanut allergy symptoms as older children as adults. It is estimated that up...

If you have a mold allergy, you’ve likely been advised to remove all sources of mold from in and around your house. But it doesn’t stop there....

You may be surprised to find that peanut butter is used to make many products. Someone who has a peanut...

More Articles

More Articles

What if, while attending a summertime family picnic, a food-allergic child shows signs of anaphylaxis. In a panicked instant, adults realize the...

Are the signs of nut allergies different than those of peanut allergies? Many people who have an allergic reaction after eating a peanut butter...

There is much buzz in the news about the potential health benefits of fecal transplants, and some of that benefit may extend to people with food...

If you or your child has a food allergy, a doctor or allergist might have talked to you about “co-factors.” Allergy co-factors are substances,...

An epinephrine auto-injector provides an emergency dose of epinephrine (adrenaline) to treat life-threatening allergic reactions. Those who have...

Oyster sauce is used for a variety of recipes, including as an earthy dressing for noodles, vegetables, and stir-fries, or as a base for other...

The high incidence of food allergy in children, and the reason many kids eventually...

Parents of children with food allergies often share tips about safe foods, allergy-friendly restaurants, and other experiences and challenges of...

Because food allergies are so common among children today, a great idea for sharing information with other classmates is to incorporate the topic...

When a child is diagnosed with peanut allergy, the implications ripple past the parents to rattle the rest of us - older siblings, grandparents,...

Your best defense against anaphylactic shock is to know what you’re up against. Anaphylaxis is a severe, life-threatening allergic reaction....

Inhalers Sometimes Contain Soy

Many people use inhalers to take the drug albuterol to help their asthma or allergies, and those with COPD...

Some people with shellfish allergy have concerns about consuming sea salt that might be contaminated with traces of shellfish. Though there are...

Nearly 25 percent of children with a peanut allergy will outgrow it. However, there is a small risk...