Bacterial Protein May Alleviate Food Allergy Symptoms

The Academy of Immunology and Microbiology says their research shows that a certain probiotic called Bifidobacterium longum KACC 91563 (BLK for short) can reduce food allergy symptoms and effects.

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Previous research has shown that probiotics in general are often good at lower food allergy symptoms. The AIM team worked to narrow down which are best, testing two strains of bacteria on food-allergic mice. The BLK strain showed the most promise in reaction change in the mice.

These work by releasing protein packets to discourage the immune system's response.

Specifically, the probiotics are working by releasing extracellular vesicles (EVs) into the intestinal tract. In BLK's case, the EVs released contain a specific protein that interacts with mast cells (which create allergic response). The interaction kills the mast cells, preventing them from triggering a response. If enough BLK is present, enough mast cells are destroyed so that the allergic response is much less severe, the research shows.

The team believes that this is an important first step towards a potential treatment for food allergies. Study results were published in the Journal of Allergy and Clinical Immunology.

Source: Eurekalert.org

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