Our daughters have been asked to participate in a highly notable Medical University study in which they would orally introduce fractions of a peanut protein to them over 16 weeks, gradully increasing their dosage until they have the protein equivalent to a whole peanut. The doses would be given on the first day of each week at the hospital under observance and then days 2 thru 13 would be given orally at home. Has anyone heard of such a study??? The thesis is that this will weaken the systems reponse to peanuts and reduce the severity of an anaphylactic response. Thoughts????
Peanut De-sensitization Study..thoughts?
Posted on: Mon, 03/15/2004 - 12:16pm
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Wow. The link below comments on previous tries with PA de-sensitization:
[url="http://www.allerg.qc.ca/peanutallergy.htm#immunoth"]http://www.allerg.qc.ca/peanutallergy.htm#immunoth[/url]
It's hard to imagine ever allowing my PA son to participate. Even if I were willing to have him participate, I know I would never agree to administering peanut protein at home, away from the hospital.
I realize somebody has to volunteer in these medical studies, but I could not let my son do it. I think PA adults who want to make that decision for themselves would be the logical candidates.
The part about doing it at home sounds far too risky.
Quote:Originally posted by Sandra Y:
[b]I think PA adults who want to make that decision for themselves would be the logical candidates.
[/b]
Hi Sandra,
I agree about the danger. I would never do this.
[i]they would orally introduce fractions of a peanut protein ...[/i]
A tiny trace of peanut protein could kill me, so there's no way I'd ever do this. It sounds very very risky to me.
[This message has been edited by erik (edited March 16, 2004).]
I know you want support to make a decision but there is no way I could convince my son to partcipate in something like this. And there is NO Way I would ever ask him to participate.
This does not sound like a good idea at all. In my research I read that they tried this in England, in an ICU and people died.
I vote no.
Peg
Chalk me up for the no's too, as well as DW.
We were also asked about being in a Peanut study, but it was for adults, so DW was invited.
She turned it down. Like Erik said, the fraction would kill her, and she'd rather not go there, kwim?
She knows her limits. But if someone else wanted to do it, more power to them. We also wouldnt put any of our kids in it. If they are teens, though, and old enough to know the ramifications of their actions... Another story.
Jason
I agree with Sandra Y that this is a study only adults should be asked to participate in at this point.
And as an adult with pa - not a chance would I do it. NO WAY!!!
Interesting theory and study. I would be highly interested in finding out the results.
But I would never let my child be a participant in it.
Absolutely not. Especially since only the first day is given under medical supervision, and the rest of the 14 days are at home!!!!!! I just can't imagine a legitimate medical research study where it would not be done the entire time under close medical supervision. How can they monitor possible reactions if they are not even there? They would have to rely upon patient/parent reports, which might not be perfectly accurate. It just doesn't sound well thought out to me.
But even if it were perfectly thought out, I wouldn't allow my daughter to participate. I agree that children should not be used in a study like this.
Quote:Originally posted by Kim M:
[b]I agree that children should not be used in a study like this.[/b]
In addition, I agree that [b]adults[/b] should not be used in a study like that either. If even a tiny trace of peanut protein can cause my death, why would anyone even consider a participating in a study like this.
Sorry, but not a snowball's chance in hell would I let my children be guinea pigs like that.
------------------
Tina
Trevor age 2 -PA
Harmony age 1 -KNA
It's a BOY!!! due June 24, 2004
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