Reaction to Apple or Keflex

Posted on: Tue, 04/22/2003 - 1:09pm
Anonymous's picture
Anonymous (not verified)

Are you allergic to apples or keflex? What kind of reaction did you have?

My son had a reaction about an hour and a half after taking a dose of Keflex which was also a few minutes after eating an apple. The doctor thinks it was from the apple - oral allergy - skin around mouth and cheeks, chin very red and lots of bumps raised about 1/8 inch each, then he rubbed his eyes and they began watering and rash spread over bridge of nose (benadryl resolved this almost immediately)...Doctor said drug allergic reaction usually is hives on legs or at least lower half of body.

I am thinking that the apple was cross contaminated with peanut or nut somehow, especially since my husband gave my son an apple when I was out, the next evening. (He wasn't around for the reaction before and had forgotten.) My son did not have a reaction to the apple this time...he also was not taking keflex since we changed his antibiotic after the reaction the day before, just in case it was drug related.

My son is allergic to penicillin (we think, because of rash that developed from amoxicillin when an infant) He has taken keflex in the past w/o incident.

He used to drink apple juice by the gallons for his first few years and rarely drank milk. A year ago he turned off apple juice and began drinking milk by the gallons.

He eats applesauce and peeled apples regularly without incident very frequently.

This year he has had one or two occasions where the area around his mouth became a little irritated after eating an apple that wasn't sliced. This also happens w/ cantaloupe, but it goes away shortly after being washed.

Any thoughts on any of this? Thanks.

Posted on: Wed, 04/23/2003 - 2:33am
McMelon's picture
Joined: 09/21/2002 - 09:00

Hey there,
My 6yo is allergic to apple skin and other tree fruits as well. His throat gets intensly itchy after he eats any fresh fruit. Applesauce is ok because the heat in processing kills the allergen. Same with canned veg, friut and tuna. So far this works for us. I would rather he could eat the fresh as it contains more nutrients and vitamins. Every time he tries he gets itchy throat. He even reacted to smell of apples while I was peeling apples for a pie recently(swollen itchy eyes and itchy throat). The allergist gave me the above info and said it is due to his tree pollen allergies. the fruits cross react with the tree pollen. I think I explained that right. Hopes this helps. Has your son been tested for environmental allergies? I would bet on the tree pollen. Melody

Posted on: Wed, 04/23/2003 - 3:06am
margaret's picture
Joined: 11/01/2000 - 09:00

I think it would be wise talk to your doctor again about the Keflex. Many people who are allergic to penicillin are also allergic to cephalosporins (I guess they are kind of like "cousins" to each other). I believe they are all in the beta lactam family. I am not a doctor or nurse, but am going by my personal experience. I am allergic to all beta lactams. There is an allergy test that your allergist can perform to confirm this.

Posted on: Wed, 04/23/2003 - 11:36am
cathlina's picture
Joined: 06/29/2001 - 09:00

There is no such thing as a "usual" drug reaction.
My daughter got a red rash from pencillin. Then her skin turned bright red after taking Keflex. Then she took Ceclor...had hives, breathing problems for five weeks. These drugs have a crossreactivity ratio of 10% to each other.
I had an allergic reaction to Zithromax last August. Swollen throat, tongue, digestive problems....10 years ago I had a reaction to
Cipro....burning skin...benadryl relieved it...but kept me in the hospital for three started burning every four hours...after three days....I itched and itched and itched and was put on predisone for 21 days.
So, what's "usual" about all these reactions?

Posted on: Sun, 04/27/2003 - 8:31pm
Claire's picture
Joined: 04/19/2000 - 09:00

Somewhere a long while ago we had posts on Apples and PA children. My son gets sick from eating apples. They were saying that it has something to dowith the Apples being exposed to the peanuts in the grocery store. I need to send my kids off to school but will come back to this thread for sure. claire

Posted on: Sun, 04/27/2003 - 11:13pm
California Mom's picture
Joined: 07/14/2000 - 09:00

From the responses you've gotten so far, it sounds like it could be either one! I have to agree that the doctor's response about a "typical" allergic reaction to a drug doesn't make much sense to me. Good luck!

Posted on: Tue, 05/13/2003 - 12:31pm
Anonymous's picture
Anonymous (not verified)

Thanks for the feedback. I am going to take my son in for a RAST on apple and possibly a skin test too...

Posted on: Fri, 05/23/2003 - 12:43pm
darthcleo's picture
Joined: 11/08/2000 - 09:00

I am not PA (my son is) but I do react to apples. Some apples, not all.
I can eat lobos without a problem, but not mcintosh (both are red apples). I get *really* sick on granny smith (the green one).
My symptoms are very itchy mouth, swollen belly, swollen lips (I look like a frog trying to attract a mate! UGH!!!), shortness of breath. I don't remember watery eyes because it's been a while since I ate an apple I shouldn't have.
Once again, cooked apples of any kind are fine.

Posted on: Fri, 05/23/2003 - 11:36pm
smack's picture
Joined: 11/14/2001 - 09:00

My pa son won't eat apples but will eat applesauce.
Sometimes you wonder if they have some innate radar for some foods that just don't cut it with them.

Posted on: Fri, 06/20/2003 - 12:35pm
Anonymous's picture
Anonymous (not verified)

Well-we had a RAST done and it seems that my son is now allergic to apples, pears, canteloupe, brocolli, and a variety of other things! In fact his levels went up on all things tested previouslly except for a slight decrease for sunflower! Anyway, I am happy he is not allergic to keflex. Sort of amazing to me that he is allergic to apples. He ate them daily for years and lived on apple juice and apple sauce when 2-5 years old.

Posted on: Mon, 07/28/2003 - 1:22pm
KarenH's picture
Joined: 09/21/2002 - 09:00

Well-I'm 32 and developed an allergy to apples at 29. I ate them lots too. With me it's Oral Allergy Syndrome, since I have really bad pollen allergies as well. Same thing though-only fresh fruit, and I get the majorly itchy throat, tongue, neck...hives...etc. Although it seems that it's gotten worse-I also react to peaches. I tried a tiny bite yesterday, wondering if my allergies may have changed. They've changed all right...for the worse. That tiny bit made me more itchy then a whole peach normally did.


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