pCheck out "The Allergy Report" on the [url="http://www.aaaai.org"]www.aaaai.org[/url] website (American Asthma Allerg.). I believe there is info. listed there re. administering this drug to help you decide how many you feel you need. If I remember correctly, for a "severe" reaction they may have to be administered every 15 minutes (up to four times in one hour in an adult) and every 15 minutes (up to three times in one hour for a child) if symptoms keep reoccuring on the way to the hospital. Your allerg. doc. is the best resource as he knows the severity of allerg. medical history of your child. Don't forget the Benedryl. It greatly increases the effectiveness of the Epi. Our doc. said makes it last twice as long./p