PA Origin

Posted on: Mon, 09/24/2007 - 1:33pm
ctmartin's picture
Joined: 07/30/2007 - 09:00

I apologize if this question has been asked before. As my daughter has been newly diagnosed with PA, I have been reading many of the wonderful resources you all have recommended and have been learning a lot. Most of the books point to a genetic predisposition for allergies, that, in turn, MAY lead to a diagnosis of PA.

Out of curiosity, how many of you out there have PA children but neither you nor your spouse have any predispositions for allergies (i.e. other food or environmental allergies, eczema or asthma)?

Neither my husband nor I have any of the above (although my husband is allergic to penicillin, which might predispose our daughter). I just wanted to know how common it is to not have an immediate family history of allergies, but still be disgnosed PA.


Posted on: Mon, 09/24/2007 - 2:13pm
cynde's picture
Joined: 12/10/2002 - 09:00

Hi, I thought DH and I had no allergies, altho I discovered a couple of years ago that I am allergic to bananas (I always just thought I hated them) with a spt. At the time of DS diagnosis, about 12 years ago.
There are allergies on both sides of the family, but nothing as severe as DS's.

Posted on: Mon, 09/24/2007 - 10:25pm
anonymous's picture
Joined: 05/28/2009 - 16:42

This is a question I often think about.
I would love to know the answer.
My husband and I have no known allergies. (environmental, food, eczema, asthma etc.)
And as far as I know, no immediate family members on either side do as well.
I've been told here in the past that the key word is "known".
As "cynde" mentioned, maybe there is a food we are allergic to and haven't discovered.

Posted on: Mon, 09/24/2007 - 11:11pm
Kathy L.'s picture
Joined: 07/30/1999 - 09:00

My 12 yo dd is pa. My husband and I have no food allergies although he does have seasonal allergies (i.e., mold, ragweed). I ate pb when pregnant and nursing both my children, but only the younger one is allergic. She's not allergic to anything else, but does have mild seasonal allergies also. No one on either side of our families has a food allergy either, but my brother seems to have sensitivities to additives.

Posted on: Mon, 09/24/2007 - 11:38pm
leers's picture
Joined: 07/09/2001 - 09:00

I personally have no allergies, hubby has environmental allergies. My hubby's brother is allergic to fish/shellfish. Those are the only known allergies in family.

Posted on: Mon, 09/24/2007 - 11:38pm
PAMomInPA's picture
Joined: 04/04/2006 - 09:00

Well my husband (and his mother) have asthma. We never thought anyone in my family had food allergies but maybe we had the groundwork there and there were just no outward signs. My sister and brother both had one child with peanut/nut allergies (and both have one child without any allergies, in one case the older is allergic, in the other, the youngest).
Like I said, there was no family history on our side but my sister never liked walnuts or pecans (she has eaten them as an adult with no reaction though) and I had a reaction to something after eating in a restaurant lasy year. My brother was a picky eater when he was young.

Posted on: Tue, 09/25/2007 - 12:04am
kelly01's picture
Joined: 03/19/2001 - 09:00

Hi ctmartin:
I have slight environmental allergies in the spring (not enough to warrent anything more than a claritin or two), and dh has no allergies.
My mother and 1 of my brothers (out of 6 kids) had asthma.
DS with PA also has asthma. I think it is probably like many things...some portion of the population has an inherited disposition, while for others it develops due to some other (unknown?) factors.

Posted on: Tue, 09/25/2007 - 12:22am
Jacobs Mom's picture
Joined: 02/12/2002 - 09:00

We have no known history of food allergies on either side. However, we do have a family history of asthma and eczema on my side of the family.
Also, I ate PB like a fiend when I was pregnant and nursing.

Posted on: Tue, 09/25/2007 - 1:04am
mistey's picture
Joined: 01/18/2004 - 09:00

I have seasonal allergies and was allergic to dairy as a child.
My ds had "hay fever" every year, but no know allergies.
We recently particiapted in a study at a children's hospital and my dh tested positive for peanut. It explained a lot of health issues that he had as a child that went undiagnosed.

Posted on: Tue, 09/25/2007 - 3:23am
ctmartin's picture
Joined: 07/30/2007 - 09:00

Hi, Everyone,
Thanks for your responses ... now I'm further confused! [img][/img]
Seriously, though ... isn't breastfeeding supposed to protect AGAINST allergies!? I had such a hard time in the beginning (like most everyone else does)but stuck with it for 14 months. It breaks my heart to think that this is in any way related to my daughter's PA! (I know that there is no conclusive evidence and only supposition, but still ...).
I understand what everyone means about "known" food alergies (meaning somewhere in our families, something may remain undiagnosed). I am just baffled b/c there is NOTHING, I mean NOTHING in any of our families (parents, siblings, selves) ... not even any health related problems that might suggest an allergy. Weird! Guess it's just one of life's many mysteries!!
Mistey, your DH tested positive for peanut but didn't know previously? Oh no ... now this will probably lead into another "is it possible to be *a little* allergic to something" argument. I guess it is, in his case. If he never had a reaction serious enough to warrant a trip to the allergist, sounds like he is only *a little* allergic to peanut.
Like I said, I'm totally confused now!! Thanks anyway everyone!!!

Posted on: Tue, 09/25/2007 - 4:02am
dulcinea's picture
Joined: 08/11/2006 - 09:00

I had the same experience as one poster's DH. I live in the Chicago area, and volunteered our family to participate in a research study at Children's Memorial. They're looking into origins of PA. They tested DH, pa son, and me for a bunch of allergens, including food, dustmites, and animals. They performed both skin and blood tests. (I have a second son who wasn't tested yet because he's too young.)
Prior to the tests, I knew I was allergic to dust and cats, but proudly proclaimed there was no food I couldn't eat. DH is severely allergic to bee stings and thought he was allergic to shellfish.
Well, I was flabbergasted at the results. DH came up negative to everything, including shellfish, on both tests. As for me, the allergies I knew about were confirmed, plus, both my skin and blood reacted to peanuts, soy, sesame, and walnuts! I couldn't believe it. I eat all of those things frequently and have no reactions at all.
Aren't allergies a mystery? I'm not allergic, yet something in my body shows a reaction. I guess that's why they say diagnosing an allergy is so complicated and they have to use not only tests but a person's actual reaction to the allergent.
DS - age 4 - allergic to peanuts, eggs, walnuts, sesame
DS - age 2 - no known allergies

Posted on: Tue, 09/25/2007 - 4:06am
dulcinea's picture
Joined: 08/11/2006 - 09:00

Quote:Originally posted by dulcinea:
DH came up negative to everything, including shellfish, on both tests.
To clarify, insect bites were not included in the research test. DH's allergy to bee stings has been confirmed in separate, previous testing.

Posted on: Tue, 09/25/2007 - 10:56am
April in KC's picture
Joined: 08/28/2006 - 09:00

My husband and I do not have food allergies. I do have a penicillin allergy, like your husband. My mother has younger brothers who are twins who both had asthma as children (but they seemed to outgrow it as they got older).
That's all we knew at the time my oldest son was diagnosed with peanut allergy five years ago.
Now - fast forward five years. I have found out that I have Celiac Disease and probably always did have it since I was a child. This is an autoimmune condition where you make antibodies to food (gluten), but it's not the same as a true IgE allergy like peanut allergy.
I also recently found out that one of my mom's brothers (one of the twins) has an allergy to pecans, but I never knew about this.
The genetic tendency is called "atopy." You can study atopy or what it means to be atopic, and you might find that either you or your husband is atopic. There are certain common physical characteristics associated with being atopic, such as having the Morgan-Dennie crease - a second crease in the skin of the lower eyelid. I do have this - it doesn't look weird or like anything you would even notice. But it's kind of fun / interesting to start noticing how many people have it.
In our generation, food allergy is unfortunately very common among atopic kids.
So - when talking about peanut allergy, it's fair to say that it's part genetic (the atopy part) and part environmental (the mystery of why so many atopic individuals now have severe food allergies).

Posted on: Tue, 09/25/2007 - 11:06am
April in KC's picture
Joined: 08/28/2006 - 09:00

I wanted to add on - I thought this linke was interesting about good allergists being able to spot allergic kids:
My oldest son has:
* allergic shiners (better most of the time now)
* Dennie-Morgan lines
* Keratosis pilaris
He had atopic eczema as a baby.
He does not have the other signs, though, as he does not have environmental allergies and nasal symptoms.

Posted on: Tue, 09/25/2007 - 11:08am
April in KC's picture
Joined: 08/28/2006 - 09:00

In absence of edit button,
Linke = link
It's the Olde English spelling. [img][/img]

Posted on: Tue, 09/25/2007 - 11:57am
Ivycosmo's picture
Joined: 09/18/2007 - 09:00

My son has a PA/TNA. No one our families (other than him) have allergies. He has a little sister who is not allergic to anything. I often wonder how this happened. Why him?
I ate PB almost obsessively when I was growing up. Used to get jars of it for Christmas! So, it was shocking to me to find out about the PA. (I guess it is always a shock, regardless)
The most credible thing I have ever read said that soy formulas could be the culprit at times. It destroys their digestive enzymes, so if they are exposed to nuts at an early age, their little bodies cannot digest it properly so they fight it off like an intruder. Thus an allergy is born. Seems credible, although I realize not a kids with PA were on soy formula.

Posted on: Tue, 09/25/2007 - 1:12pm
ctmartin's picture
Joined: 07/30/2007 - 09:00

April in KC ... funny b/c after i read your post, i was interested in "the signs" and found that same page that you have now provided a link to. it's interesting, for sure. although i have not noticed the lines, i myself have always had dark circles under my eyes which i have always attributed to heredity. i developed KP (keratitis pilaris) after pregnancy, but the doctor told me that, while i may have a predisposition to it, it was hormones that brought it out. after seeing the same site you have linked, i thought ... AHA! this is the sign telling me where the PA came from (me). but when googling "keratitis pilaris" (and, of course, from what the doctor had said) it is not related to allergies, even though it is commonly mistaken as being related to food allergies/eczema. this is just what i have been told/read ... maybe someone else has a different take on it or has heard something different?
i am mad, however, that my daughter was diagnosed with atopic dermatitis (or eczema) by one pediatrician (it wasn't severe by any means, and cleared up with 1% hydrocortisone cream), yet another pediatrician (whom i really like, unfortunately) said, "oh yeah, as long as neither you nor your husband has any history of allergies, GO AHEAD and give her PB (even though i knew better and had read everywhere to WAIT until at least 3, ESPECIALLY if baby has eczema!).
Ivycosmo ... interesting about soy. I breastfed for 14 months, but when I tried to wean my daughter she would not take milk, so we gave her soy milk (because that is all we drink). so outside of breast milk, she has primarily had soy milk (she does drink horizon vanilla milk, but that, to me, is like candy ... a treat, for sure!). and, of course, since i don't drink milk, i was drinking soy milk the whole time i breastfed her, so you may be onto something. it's strange, though, if that's true, since soy milk doesn't result in a soy allergy (my daughter tested negative and has never reacted), but a peanut allergy!

Posted on: Tue, 09/25/2007 - 4:04pm
SFMom's picture
Joined: 11/27/2006 - 09:00

For the sake of sharing info, here's mine:
Husband - Thinks he was allergic to peanuts as a child. Hates all nuts. But now (at age 45) he can eat a peanut or peanut products accidently and doesn't have any reaction. He used to vomit a lot as a child and now we think maybe it was peanuts that caused it. So perhaps he outgrew it. He was never formally tested by an allergist. He also is allergic to animal dander, dust mites, pollen and some melons. His parents had some pollen allergies, but no food allergies.
Me - I began having pollen allergies as a child. Was also allergic to melons and fresh cherries (made my throat itch and my lips swell up). Both parents are allergic to pollen, but no foods.
Older DD, age 13 - Allergic to peanuts, tree nuts, legumes, and possibly tuna. Also allergic to several classes of antibiotics. She was breastfed. I remember eating peanut butter sandwiches sometimes while I nursed her and during the pregnancy. Hindsight is 20/20, unfortunately. Before I had her, I'd never even heard of peanut allergy (DH told me he "just didn't like nuts" and never described it to me as an allergy).
Younger DD, age 11 - Allergic to peanuts, tree nuts, and legumes. She was kept away from all nuts until she accidently took a bite of a peanut butter cookie at age 5. After that, she tested positive on a skin prick test. I MAY have eaten peanut butter while pregnant with her (not sure). I found out about her older sister's peanut allergy when younger DD was an infant. She was bottle fed.

Posted on: Tue, 09/25/2007 - 4:10pm
SFMom's picture
Joined: 11/27/2006 - 09:00

Since I can't edit my post, I want to add that younger DD was bottle fed a lactose-free formula (she was having some digestive pains). It was NOT soy formula.
BTW, I believe the the proliferation of soy into our food supply is going to cause a lot more allergies in the years to come. But maybe that's a subject for another thread!

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