New Epi-pen Twinject


Just wondering if anyone has heard about the new Epi-pen Twinject that has 2 doses combined in one pen? In theory, it sounds great!! However, I am very skeptical about how the second dose is adminstered. Go to this website to see more inforamtion about the product:


More importantly go to the "how to use a Twinject section." I am not so sure that I would want my DS to have an exposed needle in his backpack or wherever he may be carrying it one day, especially as a curious child. I do think it would be ok for parents to keep in their possesion, but still very tedious putting the second dose needle together especially under a scary situation. What are your thoughts?

My husband is a pharmactist and he came up with a safer way to have 2 doses in one pen. Have the shots administered simliar to the insulin injectors that some diabetics use. I am not exactly sure how these injectors work since I am not diabetic. My husband said that you have a dial on the pen that turns for dosing and the needle protracts. Maybe, we would just need to purchase separate pen needles to replace if used. I don't know about you but the Epi-pen twin pack is very bulky and I would love some new and improved technology that is easy and SAFE to use in emergency situations.

On Apr 16, 2007

I like your husband's idea! We need not only a way to have multiple doses, but a way to have different dosages for different weights. Right now, ephinephrine autoinjectors only come in two dosages which are ideal only for 33lbs and 66lbs. Everyone else is either getting an overdose or an underdose, especially kids 40-50lbs.

About the Twinject, the second dose does seem a little complicated, but I have two Twinjects and I want to assure you that the needle is not exposed until you use the first (autoinjected) dose. For the first dose, it is very much like the Epipen.


------------------ Mom to 7 yr old PA/TNA daughter and 4 yr old son who is allergic to eggs.

On Apr 16, 2007


Originally posted by Whitney R: [b]I am not so sure that I would want my DS to have an exposed needle in his backpack or wherever he may be carrying it one day, especially as a curious child. [/b]

There is no exposed needle. Unused, the twinject looks very similar to the epi-pen. When you need to use the twinject, you take a cap off each end (unlike the epi-pen which only has a cap over one end). When the caps are both removed, there is still no exposed needle. You then use the twinject exactly the same as you would use an epi-pen. Hold against the outer thigh and press -- hold in for a count of ten -- remove. If a second dose is required, you need to carefull twist off the end with the needle. (I'm unsure whether there is a second needle inside, or if the second dose goes through the same needle -- I only have a demonstrator not the real thing.) After removing the section with the second (premeasured) dose, there is a little plastic clip (to prevent accidental injection) which needs to be removed. Then, you inject the needle, and push in the plunger.

If the second dose is not required, it cannot be kept for future use.


I googled insulin injectors, but what I found was a needleless one.

But, personally, I wouldn't want my son carrying around an epi-pen with a protractable needle. That's just way to tempting for a little boy to play with. [img][/img]

On Apr 16, 2007

Cathy, I missed your second paragraph. [img][/img] Have you ever actually used the twinject? I'm very curious whether there is a second (separate) needle for the second dose. If you have not used it, would you be willing to practice on a fruit when your twinject expires and let us know?

On Apr 16, 2007

There is a second needle for the second dose. I did a market research study on Twinject a few months ago. I hated it. The problem is that the technique for dose #1 is completely different from the technique for dose #2. I think that in the moment of a reaction, it would be confusing for teachers. Dd had pa twins at her school in kindergarten and one was found unconscious. The teacher panicked and used the epipen in the arm. I think it is just going to confuse people even more to have two different techniques for the two needles. I would not expect my 11 year old dd to be able to use a Twinject, but I do feel comfortable that she knows how to use an Epipen.

FAAN has Twinject trainers if you want to try it.

[This message has been edited by Carefulmom (edited April 16, 2007).]

On Apr 16, 2007

somewhere in the boards I wrote about my conversation with a c/s rep at Twinject. I asked her the following question:

If the first dose doesn't fire (as in, it jams or something), can the second dose be 'gotten to' by dismantling the device. Most people carry 2 or epipens in case there is an error with 1 pen (it won't fire).

She had to research it, talked to people at the lab, and got an answer.

No - if the first dose does not fire (or fire incorrectly) you CANNOT get to the second dose by taking apart the device.

She of course assured me of the success rate of firing the first pen, etc.

But, I carry 3-4 epis at a time for a few case a pen doesn't fire correctly, and if I need multiple doses.

For me, the Twinject doesn't satisfy my first criteria since I can't get to the second dose if the pen is broken and the first dose doesn't fire or jams.

That being said, I got a coupon for a Twinject, and I have a free one sitting around in the kitchen as a spare [img][/img]


------------------ 30-something survivor of severe peanut/tree nut allergy

On Apr 16, 2007

I am certain that both doses are delivered through the same needle from the same syringe. The syringe is inside the autoinjector device. After the first dose is delivered, you unscrew the top to remove the syringe. You take a little spacer off the plunger on the syringe. It is this spacer that prevents both doses from being delivered by the autoinjector. After you remove the spacer you just use the syringe to give a regular manual injection.

I have not needed to actually use my Twinjects (thank goodness!) but I had a Verus drug rep. come to our school and train the District nurse on how to use it. I was there during the training and the question of whether the same needle was used twice came up.


On Apr 17, 2007

I think most of us who've been here a while remember when TJ came out.

Honestly, Im of he belief that Dey makes a product. We've used it. We're comfy with it. Its not bulky or anything to us, threfore we won't switch. We carry 2 in a pouch.

But I suppose competition doesn't really hurt [img][/img]

Just make sure whoever is being trained IS trained on hwichever one YOU have


------------------ [b]* Beyond Obsessed * [/b]

On Apr 17, 2007


Originally posted by jtolpin: [b]But I suppose competition doesn't really hurt [img][/img] [/b]

I'll say. I don't think it's just coincidence that when twin-ject became available the epi-pen suddenly came in a better case AND easily identifiable be jr & sr doses. And, the trainer is now available for free in Canada (we used to have to purchase it).

I use epi-pen because it's what my insurance covers. I would like the insurance to cover both -- but I'm not requesting it, because I figure when the do cover the twinject, they will no longer cover the epi-pen. For schools, I prefer the epi-pen (but have already discussed with the principal regarding the twinject, so everything is in place if/when we switch to it).

On Apr 17, 2007

The twinject has only one needle. Once you take it apart, you use the same needle, remove a tab and the second dose is delivered with a plunger more like a traditional shot. It shows it on the video link of the first post. I feel okay using the twin ject, but I am less happy when I'm trying to show someone. I feel the epi pen is much easier to demonstrate.

On Apr 17, 2007

Interesting. The Twinject in the market research study I did had two needles. It was to address possible improvements. Hopefully, that is not an "improvement" they are planning to make. I did not realize the one they had me use was that different from the real one.....strange.