Negative skin prick test

Posted on: Wed, 08/21/2002 - 7:32am
amymarie's picture
Joined: 01/13/2001 - 09:00

pLooking for advice or, better yet, links to research on this issue. My son had a reaction to peanuts at just over 1 year old. He was tested-his blood test was negative his skin test was barely positive. I just had him re-tested. He is almost 3. His skin test came back negative totally-no reaction at all. The allergist stated that given the history, he does not have a peanut allergy. I was on cloud 9. then, I called FAAN to double check, someone on the phone recommended continuing carrying epis avoiding peanuts until he is 5 then doing a food challenge. While I appreciate this opinion, it seems unnecessary to continue buying epis avoiding the peanuts if he is no longer allergic. I have researched all I can have found no research indicating a negative can actually be wrong. Everything I have read is that if the blood skin prick test are negative their is no allergy. Does anyone know where this research is that indicates you can have both negative then have a reaction? Any research links is really what I am looking for. My allergist feels a food challenge is not necessary given my son's history. I wish they would perfect these tests! So frustrating. Thanks-Amy/p

Posted on: Wed, 08/21/2002 - 8:44am
DanielaW's picture
Joined: 03/22/2000 - 09:00

A negative skin prick test has a reliability of 95% accuracy (which means there's still a %5 change the result is not accurate) however I think that what FAAN told you is not unrealistic in fact waiting until his immune system is mature is frankly very advisable. I would weight the benefits vs the risks and I honestly think that waiting until he's 8 or more is a better option. Why? Because:
1) Peanuts are not such a good food nor necessary to have in order to grow healthy
2) I know it is a big hassle trying to avoid to eat peanuts but if he's not allergic the worst thing you did was depriving him for a few more years of a food he has a lifetime to enjoy.
3) Exposing him to the peanut protein when his immune system is still "maturing" can backfire.... you may remind the immune system of this protein he was once allergic to therefore giving up the possibility to outgrow it (and this happens only if you totally avoid it).
The decision is ultimately yours but if he was my son that's what I would do.... my son was allergic to milk as an infant I kept him off of milk for 2 straight years and was able to outgrow it, he's been skin tested for peanuts he's negative but not even in my wildest dreams I would even consider to let him sniff the stuff..... no way until he's much older that's what some of the allergist I've seen told me to do and did my own research as well. I hope everything will be fine for your son and good luck in making the right decision. Stay safe.

Posted on: Wed, 08/21/2002 - 12:53pm
Chris PeanutAllergy Com's picture
Joined: 04/25/2001 - 09:00

Was the recent skin test done only once or was a second skin test done right away when the first skin test was negative?
Have you had a blood test done after the skin tests came negative?
If all skin tests are negative and if you get a negative blood test are you going to contact Dr. Sampson at Mt. Sinia and/or a highly qualified board certified allergist and find out about when to do a food challenge?
Let us know what you find out and good luck!
Stay Safe,
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Stay Safe,

Posted on: Wed, 08/21/2002 - 1:32pm
san103's picture
Joined: 03/27/2000 - 09:00

I heard tha 5% of kids with negative blood and skin test will become resensitized to peanuts after repeated exposure. Interestingly enough, our 10 year old neighbor was pa, his blood and skin tests came up negative, he passed a hospital food challenge, BUT being labeled NOT allergic and after several exposures (and 1 year later) he started to react to peanuts again.

Posted on: Wed, 08/21/2002 - 2:24pm
amymarie's picture
Joined: 01/13/2001 - 09:00

Who is Dr. Sampson & how would I get in touch with him? I am in IL. The allegist I took him to is board certified. There is a lot more to this story but I just wrote it all out & then lost it, so I don't feel like retyping the whole thing-LOL. There are a lot of questions about whether he actually had a reaction or not. I want to know for sure. I am trying to do research & get the facts, which can be difficult with allergies! Do you have links for the studies indicating the immune system needs time to mature? I have not heard this. Thanks for all your posts. Amy

Posted on: Wed, 08/21/2002 - 2:51pm
Helen's picture
Joined: 05/05/2000 - 09:00

In case it's helpful, here's my child's history, which sounds somewhat similar: - My son had an ambiguous reaction to peanuts (was it really a reaction???) and subsequently tested very positive on the blood test and but negative on the skin test. On a repeat skin test, he tested positive. We waited two years, then retested - negative skin tests. Dr. did food challenge and he "passed". This was by a board certified, highly respected allergist. Either he was never allergic or he outgrew the allergy. He has since eaten peanuts without incident. Obviously, we feel VERY fortunate.

Posted on: Wed, 08/21/2002 - 2:57pm
amymarie's picture
Joined: 01/13/2001 - 09:00

Hi Helen-how old was your son when he had his reaction & how old when he tested negative? how old is he now? Sorry to be so nosy! Just curious. This does sound similar. Our first skin test (positive) was also questionable, as the staff did not know what they were doing; they reapplied the peanut product twice to the same location. I have never been so frustrated with the medical profession as dealing with PA. This allergist I recently tried was very informed & really listened. I guess I trust him more than anyone I have talked to so far. I guess the next step is the food challenge. He just felt like this was not even necessary after reviewing his history. But, how can you just give them peanuts without the challenge, as a parent, you know? We shall see. It is looking good & sounds very similar to your case!! Amy

Posted on: Wed, 08/21/2002 - 11:36pm
Carefulmom's picture
Joined: 01/03/2002 - 09:00

What I would do is to email Dr. Sampson and ask him to recommend a board certified allergist in your area. That way you know you are seeing someone whose knowledge is current. Or you could email him and ask him his opinion of your child`s situation, although it seems like it would be hard for him to give an opinion without actually seeing your child. I think Dr. Sampson is in New York. His email address is [email][/email]. Let us know what happens.

Posted on: Thu, 08/22/2002 - 1:28am
amymarie's picture
Joined: 01/13/2001 - 09:00

Carefulmom-i tried to email Dr. Sampson at the email you listed & it bounced. I doublechecked & I used the address you listed. Does anyone have another email I could try? Thanks-Amy

Posted on: Thu, 08/22/2002 - 3:28am
Carefulmom's picture
Joined: 01/03/2002 - 09:00

I have emailed him myself at that email address and gotten a response from him, so I know that address is correct.
[This message has been edited by Carefulmom (edited August 22, 2002).]

Posted on: Thu, 08/22/2002 - 8:40am
amymarie's picture
Joined: 01/13/2001 - 09:00

OOPS! I forgot the period inbetween hugh & sampson. Just re-sent my email! Thanks-Amy


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