Help with diagnosis


I am new here and am hoping to get help with a diagnosis question. I recently took my 6 year old son to an allergy doctor after his eyes swelled shut at school. He had just eaten lunch (PB sandwich) and when he got back to class he fell asleep. When the teacher checked on him, his eyes were red and swollen. He had been complaining of stomachaches and had vomited several times within the past month. After the school incident, I finally started connecting the dots and figured out that it was after eating peanuts every time. (Took me long enough to put the pieces together! We have been avoiding nuts and all symptoms are gone). The doctor did a skin test and it was negative. Due to his symptoms, he decided to do blood work as well. His test came back as "equivocal/low" at 0.26. First the doctor wanted to do a Food Challenge and then after it was all scheduled, he changed his mind and wants to do another blood test, the "uknow peanut" test. I am feeling frustrated and anxious to get definitive results. Are false negatives even a possibility? Is this new blood test going to provide any other info? Would a second opinion be something I should consider? I am scared to give him peanuts again especially for fear of a worse reaction plus he has been feeling so much better since we removed them from his diet. If anyone has any suggestions or information I would really appreciate it. Thanks so much. I am feeling a little lost

By LSUTigger on May 10, 2014

The UKnow test was great for us. It breaks down the 6 proteins in a peanut and determines a persons sensitivity to each one. 4 out if 6 cause anaphalaxis. The other 2 apparently would just cause hives and itching. Our doctor explained that it basically tells you just how cautious you need to be. Our daughter was off the bar graph with all 4 anaphalactic proteins. She will never be tested again as she will never outgrow this allergy. Our friend had the test done and his original blood test showed he was a 6 - severe PA. After a few years and then the UKnow test it was determined he grew out of his allergy somehow. They also did a food challenge in the office. He was fine.

By Mrsdocrse on May 10, 2014


I have heard about false positives, but not false negatives.... but maybe it i the case. We are having a new blood test done, it is supposed to help determine which actual protein (s) my son is allergic too. It is my understanding that if they can determine which type of protein is causing the reaction they can better predict who might outgrow it or who is more at risk for anaphylaxis (this is new, so I could be wrong). Ask your allergic about it.

I know how frustrated you must be... I would be nervous too..

By mommaoverboard on May 13, 2014

False negatives are definitely possible. The gold standard for diagnosis is a double blind oral food challenge. But do the Uknow. It may give you more information. And your allergist has, I am sure, conducted many challenges, and knows how to keep your child safe. Good luck, and hang in there!