Antibiotics prior to diagnosis with PA

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Just curious. When I was pregnant with my PA son I had to take antibiotics 1 time. Prior to Nick being diagnosed with PA he had traechelbronchitis and received a shot of rocephin, an antibiotic. We have a negative family history to allergies. I guess I'm just wondering if anybody elses PA child was on alot of antibiotis prior to their diagnosis of PA. Or if you were given antibiotics while pregnant. I've read articles where they think the kids with weakened immune systems (asthma allergies etc) might have something to do with all the antibiotics we are given. I guess I'm just curious, did you receive antibiotics while preg. or did your child receive them before being dx with PA? Kim

On Jan 6, 2001

KIM I, I thought this was a wonderful question. Now, I know that you wanted to hear from people without a family history of allergies, but I'll just come in anyway! [img]http://uumor.pair.com/nutalle2/peanutallergy/biggrin.gif[/img]

We do have a history of allergies and asthma on MY side of the family, not my husband's. However, we do not have any history of food allergies.

Jesse did not even have his first viral infection until the age of ten months and he was diagnosed with PA at 18 months. So, that leaves 8 months in there. I do not think, at that time, that he was treated with antibiotics a lot. It was more the space after his diagnosis until we moved here 2-1/2 years ago that he was over-treated with antibiotics for ear infections (before they classed them into three different categories).

Now, I did have to take antibiotics on what I consider a more frequent basis while I was pregnant with Jesse. I'm trying to remember if I was the same with my daughter or not. I somehow don't think so. I was constantly being treated for urinary tract infections while I was pregnant with Jesse and I know, on one occasion, I ended up in ER because I read that having one in your third trimester could be harmful. So, I spent hours in emerg to come home with a prescription for an antibiotic. I do know this was a persistent problem even when I conceived Jesse. My immune system is definitely weak to begin with anyway, I believe and it certainly had had a good lot of antibiotics in it during the time I conceived and carried Jesse.

I do not believe it was as severe when I carried my daughter 2 years later.

Best wishes! [img]http://uumor.pair.com/nutalle2/peanutallergy/smile.gif[/img]

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On Jan 6, 2001

I had to take an antibiotic once for an upper respiratory infection when I was about seven months pregnant. My 20 month old PA child has never taken any antibiotics at all. We have no atopic family history.

On Jan 7, 2001

I did not take any antibiotics when I was pregnant, and our son did not have any antiboitics before his pa diagnosis. We have penecillin allergies on our family, and I wanted to keep him off of them.

San

On Jan 8, 2001

Cindy, Interesting that you were treated for UTI while pg with Jesse. The one time I did take antibiotics while pg with Nick was for a UTI. In my earlier post I said we had a negative family history for allergies but forgot my mom is allergic to every antibiotic under the sun. I also try to keep my kids off antibiotics for that reason, but I do understand that sometimes they are necessary. Nick has received more antibiotics than my other son due to his asthma fortunatley he has never had an ear infection. I'm interested in anyones post about antibiotics whether family history of allergies is positive or negative.Thanks Kim

On Jan 8, 2001

KIM I., I was particularly interested in your question and what results/answers you do get because I do believe antibiotics have a lot to do with the breaking down of our immune systems and leave us more susceptible to allergies and other environmental "disorders". Now, some people may find my theory very strange, but I truly believe our bodies our breaking down because they are no longer able, in some cases, to accept the toxic air we breathe, the toxic foods we eat, etc.

I also recognize that that's very little we can do about it now. I use asthma is one of the basis for my argument. There is more asthma to-day than when I was a child and I believe it is because of the polluted air we're breathing. There are also more environmental allergies. My Mother, at 71, developed environmental allergies - not severe, but developed them regardless.

I believe there must be something written about how antibiotics do, in fact, help break down our immune systems and make us more susceptible to the infections that they are supposed to be fighting.

Also, having been through the gamut of antibiotics for both UTI and sinus infections, I also know that your body quickly becomes tolerant to a certain antibiotic so that it no longer works to get rid of the infection it was prescribed for.

At any rate, enough of my off-the-wall theory, but I do think it was a very interesting question and I am very interested in seeing what other responses you get.

As in the other thread currently going re blood type, etc. it would be interesting to see if there is even a slight co-relation between different things and PA.

Best wishes! [img]http://uumor.pair.com/nutalle2/peanutallergy/smile.gif[/img]

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On Jan 8, 2001

Well, with our strong history of allergies I don't think the antibiotics had anything to do with Logan's PA but we DID take them. I *think* I was on one round of antibiotics while pg with Logan to try to stop early labor (in case it was caused by an infection). Logan was on IV antibiotics for 5 days after he was born. He had numerous rounds of antibiotics for upper resp. infections prior to diagnosis and had 3 consecutive days of rocephin about a month before his diagnosis.

Rebekah

On Jan 9, 2001

Interesting thread.....I had penacillin in 1942 when it was pretty new and not generally available; the war and all. My PA followed very closely and its still here. No family food allergies.

On Jan 9, 2001

I was iv antibiotics due to an infection at the time my little one was born. In having to do an emergency c-section and having quit the antibiotics (LONG STORY), they put stephen on them for 2-3 days after he was born to make sure he was okay. Then at three weeks he was antibiotics because of a staph infection and in the hospital with what they *thought* would turn into encephalitis from a viral infection. He's been on antibiotics several other times in the last few months because he keeps clawing his skin open (from itching) and they are worried about infection. Most recently was about two weeks before he was diagnosed with PA. Guess that was probably a little more than you wanted... jami

On Jan 11, 2001

I was just thinking about this same thing the other day.

Lauren was *constantly* on antibiotics between ages 3mos to 1.5, for earaches mostly until her tubes were put in. She is also allergic to amoxocillian. The only antibiotic I was on when I was pregnant was for a yeast infection.

Someone, I believe it was a physician, once told me that antibiotics actually 'disable' your immune system to allow them to get what your immune system cannot. I cannot guarentee it is true either way, but this was how it was explained to me. It seems to go along with what you were saying Cindy.

I'm a bit confused though. I thought I read in some documents from FAN that a PA person's immune system was OVERactive which is why they trigger on innocous things like peanuts, milk, etc. If, say, Lauren's immune system is overactive, why then would she have been sick all the time? I would have thought she would have had an iron immune system if it was overactive.

Andrea Am I remembering incorrectly, way off-base? Someone please correct me. (I'd look it up but I'm at work.)

Andrea

On Jan 11, 2001

I find this very interesting, My PA daughter who had heart surgery when she was three and a half had a lot of antibiotics from the age of about one year to five because before the surgery she was prone to chest infections and for a while after the surgery she had quite a few chest infections for a year or so.She is nine now and thankfully doesnt get chest infections but has developed P A. I have asked the Doctors is there any connection because there wasn't any history of nut allergies in either family but off course I was told no there isn't a connections but I have serious doubts.

On Jan 11, 2001

Just curious.

How many of you have a child who was on antibiotics and developed PA and sibling who was not on antibiotics and is not PA? (

Lauren was constantly on antibiotics - developed PA. Abbey has been on antibiotics once, maybe twice in 2.5 years.

Andrea

On Jan 11, 2001

My 3 1/2 yr old pa son was on antibiotics 1 time prior to his diagnosis of his peanut allergy. Actually, his first allergic reaction was to the amoxicillan he was prescribed for an ear infection when he was 9 months old. My 20 month old son had chronic ear infections and had gone through almost every antibiotic before he had tubes put in a few weeks ago. We don't know if my younger son is pa or not but I really don't think that he is. Also, I wasn't on any antibiotics with either of my pregnancies.

On Jan 11, 2001

I was on antibiotics twice while PG. Also on IV antibiotics during labor. Our PA child was on 2 different antibiotics the first week of his life. You've got me curious as to what the antibiotics were (I can't remember now), so I'm off to dig through all our hospital records.

As an aside -- hope everyone knows to request a FULL copy of all hospital records soon after treatment of any kind -- that way you always have a complete record (or as complete as the facility kept) of the care & treatments. May be important info even years down the line. . . . EB

On Jan 16, 2001

This is very interesting. My mom and I were just talking about this yesterday. I developed a food allergy(ies) at age 25. I've used antibiotics 4 UTI's since I was about 21? My first born daughter has no known allergies and has only used Zithromax once at approx 15 mnths old, I didn't have any when pregnant with her. My other daughter had no known allergies up until 6 months old, she's allergic to soy which she has had since she was born... (she's breastfed and was occassionally supplemented w/ formula w/soy?, also foods I ate had soy) I had a UTI around when she was 5 months old & took Macrobid (supposed to be safe for babies) I didn't use antibiotics when pregnant with her. I have a very large family w/ no known foodallergies but one aunt w/ penicillin allergy. My second daughter's allergy seemed to come right after I took the antibiotic, coincidence?

It's time to do some more research! Connie [img]http://uumor.pair.com/nutalle2/peanutallergy/smile.gif[/img]

On Jan 16, 2001

I have always wondered if there was a connection between antibiotic use and the PA. It is the only thing I have been able to come up with that was 'different' between the pregnancies and births of my two children.

During my pregnancy with my PA daughter I took antibiotics for a severe respiratory infection. About a month after she was born I was put on antibiotics for a breast infection (blocked milk duct)while I was nursing her. With my nonPA daughter I didn't take antibiotics during pregnancy or while nursing her.

On Jan 16, 2001

Cayley was on antibiotics for a severe UTI (urinary tract infection) 1 year before her PA diagnosis. She had a reaction to the amoxicillin, so we took her off that medication, and as a result, the infection became antibiotic-resistant.

Nitrofurantoin was the only medicine that worked on the UTI, and she was on it for 2 months, until she could have a VCUG (a voiding-cysto-something-or-other - they insert dye in the bladder via catheter, then the patient voids the bladder while xrays are taken).

This thread has me concerned, I must say. Cayley is my 2nd child, and I took no antibiotics while I was pregnant with her, but with my 3rd child, I took antibiotics due to a severe sinus infection.

It took 3 doctors to convince me to take the antibiotics (I'm the type who watches EVERYTHING in my diet when I'm pregnant - who knew peanuts would be my downfall...). It was either antibiotics or piercing my nasal cavity, with no anaesthetic (ouch). I was going to slowly introduce allergenic-type foods to my 3rd child anyway, but now I'll be extra cautious since she was exposed in utero.

On Jan 26, 2001

I took antibiotics while pregnant with my pa son for a UTI. Before he was diagnosed with pa his doctor put him on an anitbiotic for prevention of an ear infection (we were taking a trip to florida - although he had never had ear infections before) He broke out with hives over his entire body from it. The hives lasted for almost 3 months. His doctor said they could last up to a year! When he was 17 months old (5 months after the antibiotic) we discovered his pa. I also lived on peanutbutter and fluff sandwiches while pregnant..it was all I could eat. I did not eat any kind of nut while pregnant with my daughter and was not on any antibiotic. She is 10 months old and so far no allergies. She is still so young though. All I can do is hope and pray.

On Jan 27, 2001

Cindy,

In response to your thoughts about the increase in allergies being related to more pollution. From what I understand, back in the 1980's, this was the #1 theory among researchers in this area. However, it did not prove to hold in research done after the iron curtain came down in Eastern Europe.

Researchers expected to find many, many more allergies problems in eastern Europe -- they we sure they would because pollution was so much worse in those countries. Instead they found fewer allergies and asmtha. If I remember correctly, they have found the same thing in highly polluted 3rd world nations. Since the "more pollution, more allery theory" did not hold, they developed the "too clean" theory. Highly developed nations have more allergies because we are too clean. Our immune systems are bored from the lack of invaders (no more measles, small pox, chicken pox, we all use anti-bacterial soaps, etc). So in fact the new theory does not think our immune systems are breaking down...they are becoming more sensitive.

We try to use soaps that aren't anti-bacterial now. I used to more of a clean freak, but I am much more tolerant of dirt now. I figure I'll let my son's immune system fight against good old dirt, and maybe then it will fight less against peanuts and nuts!

With regard to anti-boitics, as I said earlier, I did not take any for at least a year before I was pregnant, and my son had none before his diagnosis. Not only that, several months before I got pregnant, I did a 3 month nutritional cleansing program to restore the normal floral balance in my digestive track.

My son has had 4 ear infections. We only treated one with antiboitics (our pediatrician agreed on not treating 3, though we have had other pediatricians who pushed us to use antiboitics). The 3 untreated infections we let him immune system take care of, and he has been just fine. Antiboitics are great things for certain situations (I work for Pfizer, a huge producer of antibiotics), but I avoid them for anything that your body can clear yourself.

San

On Mar 29, 2001

Just bringing this thread back up with some interesting new data on how antibiotics used on very young children can contribute to the development of allergies.

Thanks to arachide for posting this (and other new research info) under the Research Forum.

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Excerpted from "Allergy and Asthma Report 2001", March 2001 issue DISCOVER magazine:

"A declining exposure to infections early in life has been proposed to be one mechanism accounting for the increased prevalence of allergy. Certain studies have shown an inverse association between allergic disease and the exposure to infections such as tuberculosis, measles and hepatitis A. In addition to such microbial pathogens, the principal drive for maturation of the immune system in the infant has also been recognized to be through stimulation via indigenous microflora which colonize the young child's gastrointestinal tract. Some studies have also indicated that increased antibiotic use in human infancy may be associated with an increase in developing allergies.

Since antibiotic use usually depletes the normal microflora, it is of interest to speculate that such a depletion of microflora by antibiotics may be responsible for the increased risk of developing allergies. To address this issue further, Oyama and colleagues (J Allergy Clin Immunol; January 2001) studied the effects of an antibiotic on the balance of T cells known to promote allergic responses. Interestingly, when they fed infant mice antibiotics there was an increase in IgE levels and T cells known to cause allergy."

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Check out the Research Forum for exact directions on how to read this and other abstracts on-line. The full-text version of this study is also available on-line, but you are charged a fee (the abstract is free).

On Mar 30, 2001

I am definitely convince that there is a strong connection with giving anyone a lot of antibiotics and PA.

My daughter had to have quite an amount from the age of 1 year to about 5 years and it was in the latter stage of this that it became obvious she was allergic to nuts.

On Mar 30, 2001

No family history of allergies and no antibiotics for my pa son. But if you want to talk about my other son's lactose intolerance and antibiotics....

On Mar 30, 2001

Just to confuse everyone, my non-PA daughter was on antibiotics more times than I can count from birth to age 4, just once during the 4-5 age period. No allergies.

My PA son has only been on antibiotics twice (ear infections), once before the PA diagnosis and once after.

We have no known food allergies on either side of our families, however, my DH was allergic to cats until about 3 years ago. A cat adopted us last year - he's not allergic to him. Strange.

On Apr 1, 2001

Similarly, when I was pregnant my doctor insisted (against my better judgement) that I take antibiotics for a UTI that she thought she detected from a urine test. I also had IV antibiotics during labor due to an elevated temperature. My son has PA and I wonder if those antibiotics have anything to do with it.

Neither myself nor my husband have any known allergies so the family history theory of pa is shot with us.

On Apr 2, 2001

My PA son had antibiotics prior to his first (?) exposure to peanuts. I've also heard the notion that vaccines could be the culprit.

On Apr 6, 2001

i did not use an antibiotic while i was pregnant and my son has a peanut allergy. my huband did not use antibiotics at all while he was growing up in greece and is allergic to dust mites trees and dogs. This may be from our atmosphere changing or it may simply be more doctors are recognizing allergies and asthma in people and also taking it seriously. my pediatrician told me it is possable i have had a mild case of asthma my whole life but it was not diagnosed. i do remember get pneomonia frequently as a kid. looking back now i remember times i was short of breath. being a girl. i was not encouraged to take active sports so when i felt uncomfortable i quit. I think that peoples attitudes changed. My brother was allergic to nuts as in infant. it was never a big deal. mom still bought stuff with nuts in it. my brother in law was allergic to soy beans but his mom still made soup with the beans and he just went hungry for the whole day.

On Apr 6, 2001

My son who has dairy/peanut allergies was on abx for a UTI at 2 months and I was on them while preg. with him. My 3 year old daughter who has a penicillin allergy has been on bactrim for almost 2 years for a kidney condition has no peanut allergy. I was not on abx. while preg. with her. Should I be concerned that she may develop a PA? We are peanut free at home but she does occasionally have peanut products while out alone with other family.

On Jul 22, 2001

Just bringing this back up. Kim

On Jul 23, 2001

Kim, thank you for bringing this back up. With my first son, I had a severe sinus infection days before I went into labor. I am allergic to penicillian, so I was given Cechlor. My son had ear infection after the next until he got tubes in his ears from age three to six. He ended up allergic to amoxicillian, but he is not allergic to peanuts or nuts.

With my second son, I got a severe sinus infection in my first month of pregnancy. I had checked and double checked with several doctors to make sure it was safe to take anitbotic so early in my pregnancy. I was assurred it was safe. Son #2 had a few ear infections while teething and was given cechlor once and then the second time, he broke out in such horrible purple huge hives all over his little body that I thought if someone saw him, they would report me to childrens services thinking I had beaten him up. We found out about his peanut allergy through skin tests (we had no idea about peanut allergy...we just thought he was allergic to wheat and were blown away with the news.). His cechlor reaction happened months after he was diagnosed with the peanut allergy.

What I have been trying to find and have been unsuccessful in locating is information that my aunt told me about. She said that sometime in the Spring/June 2001 that one of her New York newspapers ran an article that said cechlor as an antibotic during pregnancy is suspected to interrupt a developing fetus' immune system. Thus, the baby is more prone to developing allergies, especially the peanut allergy.

Has anyone else heard about this article? Again, I tried to do the research myself and hate asking for help, but I know my limitations in the Internet world as I am not very Surf Savvy. Thanks. Julie.

[This message has been edited by julieb (edited July 24, 2001).]

By alyelder on Jan 8, 2012

Glad you asked this question...I'm new on here. I have two children with a PA...one 28 month old and a 9 month old. Yes, I did take one antibiotic with each of my pregnancies and my first born was on several antibiotics prior to his PA diagnosis. My second born was on one antibiotic WHILE she was diagnosed with a possible PA. Still not sure if she is allergic to PA or penicillins. ~alyson

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