Action to Reaction


I'll be 44 years old tomorrow and discovered my PA in August after a PB and toast one morning and a reese's cup a couple days later. My reactions have been swallen lips and/or tung. I've also get hives and swell after contact with someone at my desk eating chinese food or my family not cleaning up after making a PB&J. These reaction usually last about 24 hours. THIS HELPS ME: I carry with me a kit. One (1) Zyrtec 10mg, two (1) benedryl and one (1) Zantac 75. And eat them as soon as I feel a reaction. Usually, I'm back to normal in just a couple of hours. The Zantac kicks in the Zyrtec or Alegra fast for some reason nobody knows.

On Oct 26, 2005

Please see your doctor to get a prescription for an epi-pen. Just because your reactions so far have been handled in the way you describe, it does not mean that the next one won't be more severe, even potentially fatal. An epi-pen is not a cure, it only buys you time until the ambulance arrives, but it can save your life.

On Oct 26, 2005

Hello BOJE, I'm 56 and like you, also have adult-onset PA. You really need to go to an allergist to be tested and to get a presecription for an epi-pen. The danger of peanut allergy is that it is unpredictable. You can have a mild reaction one time and a life-threatening reaction the next.

My doctor told me to use [url=""][/url] for information. Also, spend some time here reading, especially the forum on 'manufacturers (food) safe and unsafe'.

Best wishes.

On Oct 26, 2005

Hi BOJE, I found the following information on the Anaphylaxis-Canada web site: [url=""][/url] also a good source of information.

"What happens during a reaction? An allergic individual produces antibodies (IgE) which recognize specific proteins (allergens). These antibodies are present on the outside of mast cells and basophils. When an allergen couples with the IgE antibodies, histamine and other mediators of anaphylaxis are released from the mast cells and basophils. These mediators cause blood vessels to leak (which leads to swelling and drop in blood pressure) and airways to narrow (wheezing). Antihistamines cannot reverse all the effects of these mediators and their onset of action is too slow. Epinephrine, however, counters all the sequelae of anaphylaxis and must be given at the earliest sign. Mast cells and basophils can also release mediators via direct stimulation. This can occur with certain drugs (morphine) and exercise.

Do reactions worsen with each exposure to allergen? The severity of a reaction reflects a person's allergic sensitivity at the time of the event and the allergen load (quantity of triggering agent). Both of these can be extremely variable. Hence, ensuing reactions may be consistent, more severe or less severe. People who have had very mild reactions may suffer a severe reaction and vice versa. It is imperative to err on the side of caution and be prepared for a severe reaction at any time. "